Often in routine tests, Complete Blood Count or Haemogram is tested which gives an indication if an individual is suffering from Anaemia. Anaemia is a less understood condition
by the masses and involves a battery of tests to reveal the underlying condition. Anaemia could either be due to nutritional deficiencies, abnormal red blood cells or any other conditions like liver or kidney disorder that could lead to iron deficiency. Tests like Transferrin Saturation and TIBC (which is one of the many tests in serum iron studies) is used to assess iron deficiency or overload.
Transferrins are iron-binding blood plasma glycoproteins that control the level of free iron in biological fluids. The liver is the main site of transferrin synthesis, but other tissues and organs, such as the brain, also produce it. The main role of transferrin is to deliver iron from absorption centers in the duodenum and white blood cell macrophages to all tissues. Transferrin Saturation almost always is measured along with Total Iron Binding Capacity. The results of these two tests give complete information on anaemia.
Transferrin saturation, abbreviated as TSAT and measured as a percentage is the ratio of serum iron and total iron-binding capacity, multiplied by 100.
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