Intrinsic Factor Antibody Test

I am a returning customer
I want this for my family

Product Description

You should wait at least 48 hours after receiving a vitamin B12 injection to have a blood sample taken. The doctor may prefer not to draw a blood sample for the test within 2 weeks of an injection. Intrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of the stomach. Intrinsic factor is required for the absorption of vitamin B12 (cobalamin) from the small intestine. When enough Vitamin B12 is not absorbed, it leads to anaemia. Intrinsic Factory Antibody is not a very commonly ordered test and is usually ordered in cases of suspected anaemia and along with Serum Iron Studies. Signs and symptoms of anaemia include paleness, weakness, fatigue, numbness and a CBC (complete blood count or heamogram) reveals abnormality in Red Blood Cells.
In pernicious anemia, which is most commonly an autoimmune disease, autoantibodies directed against intrinsic factor or parietal cells themselves lead to an intrinsic factor deficiency, mal-absorption of vitamin B12, and subsequent megaloblastic anaemia.
Atrophic gastritis (severe inflammation of the stomach lining) can also cause intrinsic factor deficiency and anaemia through damage to the parietal cells of the stomach wall. Pancreatic exocrine insufficiency can interfere with normal dissociation of vitamin B12 from its binding proteins in the small intestine, preventing its absorption via the intrinsic factor complex.
When a person has a decreased vitamin B12 level and increased methylmalonic acid and homocysteine levels, an intrinsic factor antibody test is typically ordered.

FeatureValue
SpecimenSerum (Blood)
Related TestsParietal Cell Antibody, Vitamin B12, Complete Blood Count, Blood Smear, Homocysteine
Schedule Visit
Opt for Metropolis, The Pathology Specialist
The Metropolis Edge

The Metropolis Edge

  • Report trusted by Doctors.
  • Global & National Quality Accreditations – CAP (USA) and NABL , Govt. of India.
  • Guaranteed error free diagnosis.
  • Bar Coded and automated process. No room for manual errors.
  • Specific normal range for Indian population built from 33 years of experience.
  • Sample collection from home/office.
Metropolis: Experience + Expertise

Metropolis: Experience + Expertise

Over the past 3 decades we have earned the respect of doctors and patients. Today we conduct over 30 million tests annually with accuracy each year. Our repertoire extends over 4500 tests and over 100 different technologies. Our customer care is available round the clock for any queries that you may have.

Reach out to our Counsellors
Comprehensive Analysis Of Your Health