G6PD Test – Glucose 6 Phosphate Dehydrogenase Test
Glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency) also known as favism (after the fava bean) is an X-linked (hence predominantly seen in men) recessive genetic condition that predisposes to haemolysis (spontaneous destruction of red blood cells) and resultant jaundice in response to a number of triggers, such as certain foods, illness, or medication.
G6PD deficiency is characterized by abnormally low levels of glucose-6-phosphate dehydrogenase, an enzyme involved in the pentose phosphate pathway that is especially important in the red blood cell. G6PD deficiency is the most common human enzyme defect. There is no specific treatment, other than avoiding known triggers.
G6PD enzyme testing is primarily performed when an individual has signs and symptoms associated with haemolytic anaemia. Testing may be done when someone has had an episode of increased red cell destruction (haemolytic crisis) but after the crisis has resolved.
A doctor may also order the test if he is to put you under certain medications that are known to trigger haemolysis if you suffer from G6PD deficiency and are not aware of the conditions
|Related Tests||CBC, Blood Smear, Reticulocyte Count, Bilirubin, RBC Count, Hemoglobin, Heinz Body Stain|